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cycloguanil
under Proguanil
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Proguanil
Definition
: A biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.
Other names
Chloroguanide; Chlorguanid; Hydrochloride, Proguanil; Hydrochloride, Chloroguanide; Zeneca Brand of Chloroguanide Hydrochloride; Proguanil Hydrochloride; Paludrine; Chloroguanide Hydrochloride; Chloriguane; Paludrin; Bigumal; AstraZeneca Brand of Chloroguanide Hydrochloride; Astra Brand of Chloroguanide Hydrochloride
Substance
CAS Registry & name
Categories
Source
Drugs
*
cycloguanil [ 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,2,5-triazine-2,4-diamine,BN-24-10,BN2410,chlorcycloguanil,cycloguanil hydrochloride,cycloquanil ]
the active metabolite of proguanil; antifolate drug; structure in first source
516-21-2
*Proguanil
*Triazines
Pharma Action
Antimalarials
;
Folic Acid Antagonists
Biochem J 1980;187(2):533
