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meteneprost

under 16,16-Dimethylprostaglandin E2
More information in Books or onNLM PubMed
More on 16,16-Dimethylprostaglandin E2 Definition: A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and growth of experimental tumors.  DF: DIMETHYLPGE2    Other names E2, 16,16-Dimethylprostaglandin; 16,16 Dimethylprostaglandin E2; 16,16 Dimethyl PGE2; 16,16-Dimethyl-PGE2
SubstanceCAS Registry & nameCategoriesSourceDrugs*
meteneprost [ 9-deoxo-16,16-dimethyl-9-methylene-PGE2,9-deoxo-16,16-dimethyl-9-methyleneprostaglandin E2,9-deoxy-16,16-dimethyl-9-methylene-PGF2,9-methylene-16,16-dimethyl PGE2,9-methylene-PGE2 ]
  9-deoxo-9-methylene-PGEs are possible solution to PGE stability problem; stable in aqueous media from pH 1 to 14 & have biological properties similar to corresponding PGEs; cpd tested for use as early
61263-35-2 prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-methylene, (5Z,11 alpha,13E,15R)  16,16-Dimethylprostaglandin E2/*analogs & derivatives
Pharma Action Abortifacient Agents, Nonsteroidal
Adv Prostaglandin Thromboxane Res 1980;6:355

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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