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piretanide

under Sulfonamides
More information in Books or onNLM PubMed
More on Sulfonamides Definition: A group of compounds that contain the structure SO2NH2. Members of this group, also known as sulfa drugs, are derivatives of sulfanilamide, which competitively inhibit folic acid synthesis in microorganisms, and are bacteriostatic. They have been largely supplanted by more effective and less toxic antibiotics. (From Dorland, 28th ed)      Other names Mixtures, Sulfonamide; Sulfonamide Mixtures
SubstanceCAS Registry & nameCategoriesSourceDrugs*
piretanide [ 4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic acid,HOE 118 ]
  potent inhibitor of chloride transport; structure
55837-27-9   *Sulfonamides
Pharma Action Diuretics; Sodium Potassium Chloride Symporter Inhibitors
Br J Clin Pharm 6(2):129;1978; Br J Clin Pharmacol 1979;8(2):173; Br J Clin Pharmacol 4(3):392P;1977; Br J Clin Pharmacol 7(2):219;1979; Clin Pharmacol Ther 23(5):558;1978; Clin Pharmacol Ther 25(3):331;1979; Eur J Clin Pharmacol 1980;17(3):165; J Urol Nephrol (Paris) 1979;85(9):593; NZ Med J 89(629):87;1979; Nature 273(5664):678;1978; Neuropharmacology 1979;18(8-9):739; Proc Eur Dial Transplant Assoc 15:613;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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