Definition: An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
Other names Amethopterin; Sodium Salt Methotrexate; Hydrate, Methotrexate; Disodium Salt Methotrexate; Dicesium Salt Methotrexate; Mexate; Methotrexate, Sodium Salt; Methotrexate, Disodium Salt; Methotrexate, Dicesium Salt; Methotrexate, (DL)-Isomer; Methotrexate, (D)-Isomer; Methotrexate Hydrate
