encyclopedia of medical concepts
ψ
fomepizole
under Pyrazoles
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Pyrazoles
Definition
: Azoles of two nitrogens at the 1,2 positions, next to each other, in contrast with IMIDAZOLES in which they are at the 1,3 positions.
includes pyrazolines & pyrazolidines
Substance
CAS Registry & name
Categories
Source
Drugs
*
fomepizole [ 4-methylpyrazole,4-methylpyrazole monohydrochloride,Antizol,Orphan brand of fomepizole,Paladin brand of fomepizole ]
alcohol dehyrogenase inhibitor; RN given refers to parent cpd; structure
7554-65-6
*Pyrazoles
Pharma Action
Antidotes
Arch Biochem Biophys 1980;199(2):591; Biochem Med 12(3):205;1975; Biochem Pharmacol 27(1):7;1977; Biochim Biophys Acta 1980;606(2):338; Eur J Clin Invest 7(6):487;1977; J Pharmacol Exp Ther 1979;211(1):135; J Pharmacol Exp Ther 1980;213(1):70; Metabolism 27(6):631;1978; Proc Natl Acad Sci USA 1979;76(7):3499
FOMEPIZOLE
;
ANTIZOL
