encyclopedia of medical concepts
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trilostane

under Dihydrotestosterone
More information in Books or onNLM PubMed
More on Dihydrotestosterone Definition: A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.      Other names Stanolone; Androstanolone; 5 alpha-Dihydrotestosterone; 5 alpha Dihydrotestosterone; 5 alpha DHT; 17beta Hydroxy 5alpha Androstan 3 One; 17 beta Hydroxy 5 beta Androstan 3 One; Gelovit; Dihydroepitestosterone; Cuxson Brand of Androstanolone; Besins-Iscovesco Brand of Androstanolone; Berenguer Infale Brand of Androstanolone; Andractim; Anaprotin; 5-alpha-DHT; 5-alpha Dihydrotestosterone; 5 beta-Dihydrotestosterone; 17beta-Hydroxy-5alpha-Androstan-3-One; 17 beta-Hydroxy-5 beta-Androstan-3-One; beta-Hydroxy-5 beta-Androstan-3-One, 17
SubstanceCAS Registry & nameCategoriesSourceDrugs*
trilostane [ 4alpha,5-epoxy-17beta-hydroxy-3-oxoandrostane-2-carbonitrile,Modrenal,WIN 24,540,Wanskerne brand of trilostane ]
  inhibits conversion of pregnenolone to progesterone; adrenal blocking agent used in treatment of Cushing's syndrome 		13647-35-3   Dihydrotestosterone/*analogs & derivatives Oxidative Phosphorylation Coupling Factors 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors
Pharma Action Abortifacient Agents, Steroidal; Antineoplastic Agents; Enzyme Inhibitors 		Endocrinology 103(4):1411;1978; Endocrinology 97(1):136;1975; Fertil Steril 1979;32(4):464; J Endocrinol 76:293;1978; Steroids 32(2):257;1978 MODRASTANE

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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