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tryptoline

under Carbolines
More information in Books or onNLM PubMed
More on Carbolines Definition: A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles.      Other names Beta Carbolines; Pyrido(4,3-b)Indoles; Beta-Carbolines
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tryptoline [ 1,2,3,4-tetrahydro-beta-carboline,9H-1,2,3,4-tetrahydropyrido(3,4-b)indole,THbetaC,noreleagnine,tetrahydro-beta-carboline,tetrahydronorharmane,triptoline,tryptoline hydrochloride,tryptoline monohydrochloride ]
  neurotoxic factor that may be involved in development of Parkinson's disease; enzymatic prep from human brain converts tryptamine to tryptoline; RN given refers to parent cpd; structure
16502-01-5 2,3,4,9-tetrahydro-1H- pyrido(3,4-b)indole  *Carbolines
Pharma Action Neurotoxins
Arch Gen Psychiatry 31(6):862;1974; Biochem Biophys Res Commun 87(1):146;1979; FEBS Lett 98(1):96;1979; Naunyn Schmiedebergs Arch Pharmacol 292(1):93;1976; Naunyn Schmiedebergs Arch Pharmacol 298(2):83;1977; Naunyn Schmiedebergs Arch Pharmacol 303(3):229;1978; Naunyn Schmiedebergs Arch Pharmacol 305(2):135;1978; Pharm Acta Helv 1979;54(12):349; Pharmacol Biochem Behav 5(4):383;1976; Proc West Pharmacol Soc 19:331;1975; Science 187(4179):853;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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