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ψ
ψ

perhydrohistrionicotoxin

under Amphibian Venoms
More information in Books or onNLM PubMed
More on Amphibian Venoms Definition: Venoms produced by frogs, toads, salamanders, etc. The venom glands are usually on the skin of the back and contain cardiotoxic glycosides, cholinolytics, and a number of other bioactive materials, many of which have been characterized. The venoms have been used as arrow poisons and include bufogenin, bufotoxin, bufagin, bufotalin, histrionicotoxins, and pumiliotoxin.  /antag permitted but consider also ANTIVENINS; /enzymol permitted; coord IM with specific amphibian (IM or NIM)    Other names Toad Venoms; Frog Venoms; Venoms, Toad; Venoms, Frog; Venoms, Amphibian; Venom, Toad; Venom, Frog; Venom, Amphibian; Toad Venom; Frog Venom; Amphibian Venom
SubstanceCAS Registry & nameCategoriesSourceDrugs*
perhydrohistrionicotoxin [ 2-epi-(+/-)-perhydrohistrionicotoxin,H(12)-HTX,perhydrohistrionicotoxin, (6alpha(S*),7beta,8alpha)-(+-)-isomer ]
  RN given refers to (6R-(6 alpha(R*),7 beta,8 alpha))-isomer; structure 		40709-29-3   *Amphibian Venoms Neurotoxins
Pharma Action Parasympatholytics 		Biochem Biophys Res Commun 77(4):1347;1977; Biochemistry 17(25):5474;1978; Biochemistry 18(10):1868;1979; J Physiol 1979;297:423; Mol Pharmacol 13:1;1977; Proc Natl Acad Sci USA 70(3):949;1973; Proc Natl Acad Sci USA 74(5):2172;1977; Proc Natl Acad Sci USA 75(3):1596;1978; Proc Natl Acad Sci USA 76(6):2567;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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