4-aminopyrazolo(3 (definition)

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ψ	4-aminopyrazolo(3,4-d)pyrimidine under Adenine

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Definition: A purine base and a fundamental unit of ADENINE NUCLEOTIDES.

/biosyn/physiol permitted

Other names Vitamin B 4; B 4, Vitamin; 4, Vitamin B

Substance	CAS Registry & name	Categories	Source	Drugs*
4-aminopyrazolo(3,4-d)pyrimidine [ 4APP-4,aminopurinol ] adenine analog which suppresses growth of E coli & Bacillus cereus; inhibits cell growth & purine biosynthesis in rat hepatoma	2380-63-4	Adenine/analogs & derivatives Pharma Action* Anticholesteremic Agents; Antiprotozoal Agents	Biochem Pharmacol 23(22):1399;1974; Can J Biochem 55(1):110;1977; J Am Chem Soc 99(22):7257;1977; J Biol Chem 252(11):3652;1977; J Biol Chem 252(5):1771;1977; J Lipid Res 1979;20(7):879; Proc Natl Acad Sci USA 73(8):2564;1976; Proc Natl Acad Sci USA 74(4):1421;1977; Rec Prog Horm Res 1979;35:224; Scand J Clin Lab Invest 38(7):643;1978; Science 193(4256):903;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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4-aminopyrazolo(3,4-d)pyrimidine