Definition: Usually 12,13-epoxytrichothecenes, produced by Fusaria, Stachybotrys, Trichoderma and other fungi, and some higher plants. They may contaminate food or feed grains, induce emesis and hemorrhage in lungs and brain, and damage bone marrow due to protein and DNA synthesis inhibition.
Other names Trichothecene Epoxides; Epoxytrichothecenes; Epoxides, Trichothecene
Appl Environ Microbiol 1979;38(2):344; Appl Environ Microbiol 35(1):206;1978; Biochim Biophys Acta 383(2):207;1975; Biochim Biophys Acta 454(2):273;1976; Can Vet J 19(10):267;1978; Cancer 42(1):23;1978; Cancer Chemother Pharmacol 1(1):17;1978; Cancer Chemother Pharmacol 1(2):91;1978; Cancer Clin Trials 1978;1(4):297; Cancer Res 38(10):3304;1978; Cancer Treat Rep 1979;63(11-12):1993; Cancer Treat Rep 1979;63(11-12):2015; Cancer Treat Rep 62(10):1497;1978; Chem Biol Interact 10(5):339;1975; J Assoc Off Anal Chem 55(4):895;1972; J Assoc Off Anal Chem 61(4):801;1978; J Nat Cancer Inst 52(1):113;1974; J Pharm Sci 67(12):1768;1978; Planta Med 34(3):231;1978; Poultry Sci 57(3):807;1978